About FAIR-TPs
Explore FAIR transformation products & metabolites collated from open and trusted sources
FAIR-TPs offers a clean interface to literature-based transformations, with transparent provenance and reuse in mind.
Atrazine
Ammeline
Propachlor
What is FAIR-TPs?
An interface to explore transformations and metabolites with openness, traceability, and reuse at its core.
Data sources
Combined annotations from ChEMBL and NORMAN-SLE, integrating biochemical and environmental transformation data.
Contribute
Share new transformations via the FAIR template CSV and Contact us to integrate your data.
Browsing FAIR Transformation Product Information with FAIR-TPs
We introduce FAIR-TPs: an open, literature-based resource to browse transformation products and metabolites, connect precursor→product pathways, and explore transformation networks with clear provenance.
Collect
Aggregate transformations from public sources with clear provenance.
Visualize
Browse full reaction networks and direct neighbours interactively.
Link
Graph-connect precursors, products, enzymes, and evidence.
Explore
Browse, filter, and export subsets for analysis and reuse.
FAIR-TPs is a website to browse transformation products (TPs) and metabolites documented in literature, collated from several open resources. Currently, it is a user interface to the full dataset of Transformations in PubChem, which is a combined dataset formed from transformations associated with ChEMBL and the NORMAN-SLE. The code used to collate this data is available on the ECI GitLab, and the contents are summarized in this README.
The term "transformation product" is used instead of "metabolite" since many of the transformations (reactions) come from environmental data, where they may be biotic or abiotic reactions (and thus not technically always the result of metabolism). Several reactions also involve treatment techniques - in other words, they may not be expected to occur under natural conditions. The NORMAN-SLE datasets are described in Mohammed Taha et al (2022) DOI: 10.1186/s12302-022-00680-6, while a Findable, Accessible, Interoperable, Reusable (FAIR) template to contribute data is available here, as described in Schymanski and Bolton (2022) DOI: 10.1093/exposome/osab006. Please see the contact page for details on how to contribute data.
