About FAIR-TPs

Explore FAIR transformation products & metabolites collated from open and trusted sources

FAIR-TPs offers a clean interface to literature-based transformations, with transparent provenance and reuse in mind.

Atrazine Ammeline Propachlor

Compounds

Reactions

Primary sources

What is FAIR-TPs?

An interface to explore transformations and metabolites with openness, traceability, and reuse at its core.

Data sources

Combined annotations from ChEMBL and NORMAN-SLE, integrating biochemical and environmental transformation data.

Contribute

Share new transformations via the FAIR template CSV and Contact us to integrate your data.

Newly Published

Browsing FAIR Transformation Product Information with FAIR-TPs

Bashir Mayahi, Emma Palm, Emma Schymanski

Published: 2026 DOI: 10.1021/acsenvironau.5c00314

We introduce FAIR-TPs: an open, literature-based resource to browse transformation products and metabolites, connect precursor→product pathways, and explore transformation networks with clear provenance.

Read Full Paper

Collect

Aggregate transformations from public sources with clear provenance.

Visualize

Browse full reaction networks and direct neighbours interactively.

Link

Graph-connect precursors, products, enzymes, and evidence.

Explore

Browse, filter, and export subsets for analysis and reuse.

About the Data

Exploring the underlying datasets, terminology, and open-source provenance behind FAIR-TPs.

The Core Dataset

FAIR-TPs is a user interface to browse transformation products (TPs) and metabolites from open resources. It serves the full dataset of Transformations in PubChem, formed from transformations associated with ChEMBL and the NORMAN-SLE.

Metabolite vs. TP

The term "transformation product" (TP) is used instead of "metabolite" because many reactions stem from environmental data (biotic or abiotic), or involve treatment techniques. Therefore, they are not always the result of biological metabolism and may not naturally occur.

Key Publications

The NORMAN-SLE datasets are detailed in Mohammed Taha et al. (2022) 10.1186/s12302-022-00680-6. The Findable, Accessible, Interoperable, Reusable (FAIR) template used to submit data is described in Schymanski and Bolton (2022) 10.1093/exposome/osab006.

Open Code & Contribute

The code used to collate this data is available on the ECI GitLab, with contents summarized in the README. We welcome new contributions via our FAIR template.